Evolution of Liver Dysfunction in Multitransfused Haemophiliacs
نویسندگان
چکیده
منابع مشابه
Hepatitis B virus infection in multitransfused haemophiliacs.
A longitudinal study of 44 haemophilic children, all in a treatment programme with factor concentrates, was undertaken to evaluate the occurrence, characteristics, and evolution of hepatitis B virus (HBV) infection. Twenty four children (55%) (group I) showed signs of HBV infection, while 20 (45%) (group II) did not. Age at onset of treatment, number of infusions, and total amount of concentrat...
متن کاملA clinicopathological study of liver disease in haemophiliacs.
Chronic liver disease is not often reported in patients with haemophilia. Although a high incidence of abnormal liver function tests has been reported, the clinical significance of these findings and their relation to chronic liver disease cannot be established without a liver biopsy. The results of this procedure, carried out in 11 patients with severe haemophilia A and B, in whom SGOT had bee...
متن کاملLiver function in Edinburgh haemophiliacs: a five-year follow-up.
Liver function was assessed in 38 Edinburgh haemophiliacs. Results before the introduction of NHS intermediate factor VIII concentrate from 1974 onwards were compared with values in 1979. Measurements of serum bile salts in 16 patients as well as conventional liver function tests gave useful evidence of deranged liver function. Deterioration over the five-year follow-up period was seen only in ...
متن کاملLiver transplantation for haemophiliacs with hepatitis C cirrhosis.
BACKGROUND Experience of liver transplantation in haemophiliacs with end stage hepatitis C liver disease is limited and particularly difficult questions are raised when there is also HIV infection. AIMS This is the first report in Great Britain to describe the operative replacement therapy and initial outcome in four haemophiliacs with end stage HCV cirrhosis. PATIENTS Two patients had fact...
متن کاملMarkers of Viral Infection in Haemophiliacs
Seroprevalence of Hepatitis B surface antigen (HbsAg), anti-HCV IgG and anti-HIV IgG was determined in 100 people with Haemophilia (PWH), registered with Haemophilia Patient Welfare Society (HPWS), Lahore Zone, Pakistan. The study shows that none of the PWH were infected with HIV whereas a modest 4% were positive for HbsAg. However, there was a high level of anti-HCV seropositivity (56%) in our...
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ژورنال
عنوان ژورنال: Pathophysiology of Haemostasis and Thrombosis
سال: 1981
ISSN: 1424-8832,1424-8840
DOI: 10.1159/000214540